Speaker
Description
In this work, we continue the reports on the functionalization of the Poly(L-lactic) acid (PLLA) (biocompatible and biodegradable semicrystalline synthetic polymer) surface for bone tissue engineering according to the task started in Refs. [1-3]. Here we report the series of thin films investigated using the scanning probe microscopy technique (SPM) implemented in atomic force (AFM), piezoresponse (PFM), and Kelvin-probe (KPFM) modes. The samples were deposited by spin coating technique (2,5% w/w solution) on 316L SS substrate (previously functionalized with thermal treatment (500 ºC for 2 hours) and silanization APTES (60 min) procedures) were crystallized (180 ºC for 3 min followed by 120 ºC for 45 min). The correlated results of topography and PFM scan images indicate the in-phase adjacent out-of-plane and in-plane PFM responses that imply the piezo- and ferroelectric nature of the PLLA thin films as measured at the nano- and microscale levels. An application of square-shaped and box-in-box DC bias voltage/BV gives rise to a work function redistribution measured as sharp contrast in KPFM response and substantial impact in both OOP and IP PFM signals. The DC BV-changed KPFM signal is associated with the induced uncompensated dipole moments (induced piezoelectric response). The obtained results provide advanced prospects of PLLA towards technological applications as the scaffold for tissue regeneration.
References
[1] Barroca N, Daniel-Da-Silva A L, Vilarinho P. M., and Fernandes M. H. V., Acta Biomater.,6,(2010),3611.
[2] Marote A, Barroca N, Vitorino R, M. Silva R, H.V. Fernandes M, M. Vilarinho P, A.B. da Cruz e Silva O and I. Vieira S, AIMS Mol. Sci.3,(2016),661–82.
[3] Barroca N, Vilarinho P. M, Fernandes M H V., Sharma P, and Gruverman A, Appl. Phys. Lett,101,(2012),1–5.
| Speaker Country | Portugal |
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