EUROPEAN CONGRESS AND EXHIBITION ON ADVANCED MATERIALS AND PROCESSES - EUROMAT 2021

Biodegradable implants constitute a new generation of biomedical materials that are being developed to assist the tissue healing processes and gradually corrode and degrade in-vivo after their function is being fulfilled. Among others, Fe-based alloys show promising mechanical properties such as ductility and high ultimate strength. However, the corrosion rate of those implants is relatively...

Magnesium alloys exhibit promising properties as bone implant materials due to their biodegradability, non-toxicity and mechanical properties. Compared to steel and Ti, Mg implants can be fully re-absorbed by the human body and the mechanical properties are similar to that of the bones and do not lead to stress shielding. Porous scaffolds are ideal structures for bone regeneration as they...

Twinning-induced plasticity (TWIP) steels have been recently proposed for manufacturing biodegradable stents. Thanks to their exceptional mechanical properties, closely resembling those of the commonly used L605 Co-Cr alloy, thinner structures can finally be targeted. However, in vivo studies on Fe-based alloys reported that a compact layer of phosphates formed on the surface during...

Metallic biodegradable alloys constitute a new class of biomaterials for temporary applications. Fe-Mn-C steels are particularly attractive for the production of very thin implants, including stents, mainly due to their outstanding mechanical properties. To cut the complex geometry of stents, laser processing is considered the gold standard, even if it results in debris and slag materials on...

Magnesium (Mg) is investigated as a powerful alternative to state-of-the-art titanium implants for temporary bone support, due to its biodegradability, biocompatibility and mechanical properties. However, certain processes occurring during Mg degradation are still unclear, in particular the relative importance of transport phenomena vs. micro-galvanic corrosion. Mechanistic and computational...

Metallic programmable mechanical metamaterials implement the bioinspired functionalities, for example, adaptability enabled by logical calculations and memory, in hierarchical structured metallic materials, and create huge design space for mechanically robust and functionally smart materials for biomedical, environmental, energy-related applications. The programmability of these materials...

Fetuin is a high abundant serum glycoprotein and a major non-collagenous protein, essential for biomineralization. The inductive effect on bone formation, thus mineralization, is one of the major benefits of magnesium (Mg)-based biomaterials for orthopaedic applications. Due to the high affinity of fetuin to calcium (Ca)-salts, fetuin might have a synergistic effect with Mg-based biomaterial...

Multifunctional materials based on a combination of permanent and degradable metals open new perspectives for medical implants combining osseo-conductivity and drug-delivery functions, which can significantly decrease the number of implants´ revision. In this work, the hybrid magnesium-titanium materials were produced via sintering and the properties of the permanent titanium component before...

Despite Ti alloys are biocompatible and non-allergenic, their use in blood contact applications including stent was rarely reported, mainly due to their low strength-ductility trade-off. In this work, two strengthening strategies were investigated to achieve Ti alloys with required mechanical properties for stent applications. The first tackled the increase of oxygen content in the TWIP...

Ti6Al4V is the most widely used material for implant applications among titanium alloys that offer unique advantages over 316L stainless steels and Co-based alloys because of its low weight and high corrosion resistance. However, various interactions between implants and the biological environment can lead to the release of Al and V ions into the body fluid and raise long-term biocompatibility...

The structural integrity of Nitinol stents is of great importance for the successful deployment and life-time service in the patients receiving stent implantation. Over years, problems caused by unknown reason keep being reported from industrial quality control and clinical operations, such as unexpected corrosion susceptibility, strut damage and incomplete self-expansion. In order to optimize...

In the race towards the perfect implantable material, titanium and its alloys have been subjected to a great number of different surface treatments. A fundamental step in this way is to understand how biological fluids and proteins interact with biomaterials, since the layer of adsorbed proteins strongly influences the cell-surface interfacial region. In this work, c.p. Ti and Ti6Al4V alloy...